Buy Oxycodone 30mg online USA.For the naturally occurring peptide hormone, see Oxytocin.

Clinical data
Trade namesOxyContin, Endone, others
Other namesEukodal, eucodal; dihydrohydroxycodeinone, 7,8-dihydro-14-hydroxycodeinone, 6-deoxy-7,8-dihydro-14-hydroxy-3-O-methyl-6-oxomorphine[1]
License dataUS DailyMedOxycodone
AU: C[2]
Routes of
By mouth, sublingual, intramuscular, intravenous, intranasal, subcutaneous, transdermal, rectal, epidural[4]
ATC codeN02AA05 (WHO)
N02AA55 (WHO) N02AJ18 (WHO) N02AJ19 (WHO) N02AA56 (WHO) N02AJ17 (WHO)
Legal status
Legal statusAU: S8 (Controlled drug) DE: Anlage III (Special prescription form required) UK: Class A US: Schedule II
Pharmacokinetic data
BioavailabilityBy mouth: 60–87%[5][6]
Protein binding45%[5]
MetabolismLiver: mainly CYP3A, and, to a much lesser extent, CYP2D6 (~5%);[5] 95% metabolized (i.e., 5% excreted unchanged)[8]
MetabolitesNoroxycodone (25%) [7][8]
Noroxymorphone (15%, free and conjugated)[7][8]
Oxymorphone (11%, conjugated)[7][8]
• Others (e.g., minor metabolites)[8]
Onset of actionIR: 10–30 minutes[6][8]
CR: 1 hour[9]
Elimination half-lifeBy mouth (IR): 2–3 hrs (same t1/2 for all ROAs)[8][6]
By mouth (CR): 4.5 hrs[10]
Duration of actionBy mouth (IR): 3–6 hrs[8]
By mouth (CR): 10–12 hrs[11]
ExcretionUrine (83%)[5]

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IUPAC name
CAS Number76-42-6 
PubChem CID5284603
KEGGD05312 as HCl: D00847 
CompTox Dashboard (EPA)DTXSID5023407
ECHA InfoCard100.000.874
Chemical and physical data
Molar mass315.369 g·mol−1
3D model (JSmol)Interactive image
Melting point219 °C (426 °F)
Solubility in water166 (HCl)

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Oxycodone (sold under the brand names Roxicodone and OxyContin, which is the extended release form, among others) is an opioid medication used for treatment of moderate to severe pain. It is highly addictive[12] and is commonly used recreationally by people who have an opioid use disorder.[13][14] It is usually taken by mouth, and is available in immediate-release and controlled-release formulations.[13] Onset of pain relief typically begins within fifteen minutes and lasts for up to six hours with the immediate-release formulation.[13] In the United Kingdom, it is available by injection.[15] Combination products are also available with paracetamol (acetaminophen), ibuprofen, naloxone, naltrexone, and aspirin.[13]Buy Oxycodone 30mg online USA

Common side effects include euphoria, constipation, nausea, vomiting, loss of appetite, drowsiness, dizziness, itching, dry mouth, and sweating.[13] Severe side effects may include addiction, dependence, aggression, mania or depression, hallucinations, hypoventilation, gastroparesis, bradycardia, and hypotension.[13] Those allergic to codeine may also be allergic to oxycodone.[13] Use of oxycodone in early pregnancy appears relatively safe.[13] Opioid withdrawal may occur if rapidly stopped.[13] Oxycodone acts by activating the μ-opioid receptor.[16] When taken by mouth, it has roughly 1.5 times the effect of the equivalent amount of morphine.[17]

Oxycodone was first made in Germany in 1916 from Thebaine.[18] It is on the World Health Organization’s List of Essential Medicines.[19] It is available as a generic medication.[13] In 2019, it was the 49th most commonly prescribed medication in the United States, with more than 14 million prescriptions.[20][21] A number of abuse-deterrent formulations are available, such as in combination with naloxone or naltrexone.[14][22]

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